Picture naming test through the prism of cognitive neuroscience and linguistics: adapting the test for cerebellar tumor survivors-or pouring new wine in old sacks?

A picture naming test (PNT) has long been regarded as an integral part of neuropsychological assessment. In current research and clinical practice, it serves a variety of purposes. PNTs are used to assess the severity of speech impairment in aphasia, monitor possible cognitive decline in aging patients with or without age-related neurodegenerative disorders, track language development in children and map eloquent brain areas to be spared during surgery. In research settings, picture naming tests provide an insight into the process of lexical retrieval in monolingual and bilingual speakers. However, while numerous advances have occurred in linguistics and neuroscience since the classic, most widespread PNTs were developed, few of them have found their way into test design. Consequently, despite the popularity of PNTs in clinical and research practice, their relevance and objectivity remain questionable. The present study provides an overview of literature where relevant criticisms and concerns have been expressed over the recent decades. It aims to determine whether there is a significant gap between conventional test design and the current understanding of the mechanisms underlying lexical retrieval by focusing on the parameters that have been experimentally proven to influence picture naming. We discuss here the implications of these findings for improving and facilitating test design within the picture naming paradigm. Subsequently, we highlight the importance of designing specialized tests with a particular target group in mind, so that test variables could be selected for cerebellar tumor survivors.

Applicability and usefulness of pupillometry in the study of lexical access. A scoping review of primary research.

Pupil dilation has been associated with the effort required to perform various cognitive tasks. At the lexical level, some studies suggest that this neurophysiological measure would provide objective, real-time information during word processing and lexical access. However, due to the scarcity and incipient advancement of this line of research, its applicability, use, and sensitivity are not entirely clear. This scoping review aims to determine the applicability and usefulness of pupillometry in the study of lexical access by providing an up-to-date overview of research in this area. Following the PRISMA protocol, 16 articles were included in this review. The results show that pupillometry is a highly applicable, useful, and sensitive method for assessing lexical skills of word recognition, word retrieval, and semantic activation. Moreover, it easily fits into traditional research paradigms and methods in the field. Because it is a non-invasive, objective, and automated procedure, it can be applied to any population or age group. However, the emerging development of this specific area of research and the methodological diversity observed in the included studies do not yet allow for definitive conclusions in this area, which in turn does not allow for meta-analyses or fully conclusive statements about what the pupil response actually reflects when processing words. Standardized pupillary recording and analysis methods need to be defined to generate more accurate, replicable research designs with more reliable results to strengthen this line of research.

The DDQ-30, a new naming-from-definition test: Normative data for the adult French-Quebec population and validation study in mild cognitive impairment and Alzheimer's disease.

Assessing naming abilities is a standard clinical procedure for adults and is usually carried out using picture naming tests. However, the use of picture naming tests can have limitations, as people may have visual impairments that can affect the validity of the measurement. This article introduces the DDQ-30, a new naming-from-definition test for detecting anomia in people with visual-perceptual limitations. The article describes three studies. Study 1 focused on the developmental phase of the DDQ-30. In Study 2, healthy participants and individuals with mild cognitive impairment or Alzheimer's disease were assessed with the DDQ-30 to determine its predictive validity. Study 3 examined a group of adults and older French-speaking Quebecers to obtain normative data. The DDQ-30 effectively differentiated between AD and healthy participants. In addition, normative data were collected on 251 participants aged 50 years and older. Analyses showed that age and educational level were significantly related to performance on the DDQ-30. The DDQ-30 fills an important gap and promises to help clinicians and researchers better detect anomia in people with visual impairment.

Information entropy facilitates (not impedes) lexical processing during language comprehension.

It is well known that contextual predictability facilitates word identification, but it is less clear whether the uncertainty associated with the current context (i.e., its lexical entropy) influences sentence processing. On the one hand, high entropy contexts may lead to interference due to greater number of lexical competitors. On the other hand, predicting multiple lexical competitors may facilitate processing through the preactivation of shared semantic features. In this study, we examined whether entropy measured at the trial level (i.e., for each participant, for each item) corresponds to facilitatory or inhibitory effects. Trial-level entropy captures each individual's knowledge about specific contexts and is therefore a more valid and sensitive measure of entropy (relative to the commonly employed item-level entropy). Participants (N = 112) completed two experimental sessions (with counterbalanced orders) that were separated by a 3- to 14-day interval. In one session, they produced up to 10 completions for sentence fragments (N = 647). In another session, they read the same sentences including a target word (whose entropy value was calculated based on the produced completions) while reading times were measured. We observed a facilitatory (not inhibitory) effect of trial-level entropy on lexical processing over and above item-level measures of lexical predictability (including cloze probability, surprisal, and semantic constraint). Extra analyses revealed that greater semantic overlap between the target and the produced responses facilitated target processing. Thus, the results lend support to theories of lexical prediction maintaining that prediction involves broad activation of semantic features rather than activation of full lexical forms.

Characterizing language production across modalities.

ABSTRACTThis study investigates factors influencing lexical access in language production across modalities (signed and oral). Data from deaf and hearing signers were reanalyzed (Baus and Costa, 2015, On the temporal dynamics of sign production: An ERP study in Catalan Sign Language (LSC). Brain Research, 1609(1), 40-53. https://doi.org/10.1016/j.brainres.2015.03.013; Gimeno-Martínez and Baus, 2022, Iconicity in sign language production: Task matters. Neuropsychologia, 167, 108166. https://doi.org/10.1016/j.neuropsychologia.2022.108166) testing the influence of psycholinguistic variables and ERP mean amplitudes on signing and naming latencies. Deaf signers' signing latencies were influenced by sign iconicity in the picture signing task, and by spoken psycholinguistic variables in the word-to-sign translation task. Additionally, ERP amplitudes before response influenced signing but not translation latencies. Hearing signers' latencies, both signing and naming, were influenced by sign iconicity and word frequency, with early ERP amplitudes predicting only naming latencies. These findings highlight general and modality-specific determinants of lexical access in language production.

Predictability Associated With Reduction in Phonetic Signals Without Semantics-The Case of Glossolalia.

Glossolalia can be regarded as an instance of speech production in which practitioners produce syllables in seemingly random sequences. However, a closer inspection of glossalalia's statistical properties reveals that sequences show a Zipfian pattern similar to natural languages, with some syllables being more probable than others. It is well established that statistical properties of sequences are implicitly learned, and that these statistical properties correlate with changes in kinematic and speech behavior. For speech, this means that more predictable items are phonetically shorter. Accordingly, we hypothesized for glossolalia that if practitioners have learned a serial pattern in glossolalia in the same manner as in natural languages, its statistical properties should correlate with its phonetic characteristics. Our hypothesis was supported. We find significantly shorter syllables associated with higher syllable probabilities in glossolalia. We discuss this finding in relation to theories about the sources of probability-related changes in the speech signal.

Predictions about prosody facilitate lexical access: Evidence from P50/N100 and MMN components.

Research into the neural foundation of perception asserts a model where top-down predictions modulate the bottom-up processing of sensory input. Despite becoming increasingly influential in cognitive neuroscience, the precise account of this predictive coding framework remains debated. In this study, we aim to contribute to this debate by investigating how predictions about prosody facilitate speech perception, and to shed light especially on lexical access influenced by simultaneous predictions in different domains, inter alia, prosodic and semantic. Using a passive auditory oddball paradigm, we examined neural responses to prosodic changes, leading to a semantic change as in Dutch nouns canon ['kaːnɔn] 'canon' vs kanon [kaː'nɔn] 'cannon', and used acoustically identical pseudowords as controls. Results from twenty-eight native speakers of Dutch (age range 18-32 years) indicated an enhanced P50/N100 complex to prosodic change in pseudowords as well as an MMN response to both words and pseudowords. The enhanced P50/N100 response to pseudowords is claimed to indicate that all relevant auditory information is still processed by the brain, whereas the reduced response to words might reflect the suppression of information that has already been encoded. The MMN response to pseudowords and words, on the other hand, is best justified by the unification of previously established prosodic representations with sensory and semantic input respectively. This pattern of results is in line with the predictive coding framework acting on multiple levels and is of crucial importance to indicate that predictions about linguistic prosodic information are utilized by the brain as early as 50 ms.

Word frequency has similar effects in picture naming and gender decision: A failure to replicate Jescheniak and Levelt (1994).

Word frequency plays a key role in theories of lexical access, which assume that the word frequency effect (WFE, faster access to high-frequency than low-frequency words) occurs as a result of differences in the representation and processing of the words. In a seminal paper, Jescheniak and Levelt (1994) proposed that the WFE arises during the retrieval of word forms, rather than the retrieval of their syntactic representations (their lemmas) or articulatory commands. An important part of Jescheniak and Levelt's argument was that they found a stable WFE in a picture naming task, which requires complete lexical access, but not in a gender decision task, which only requires access to the words' lemmas and not their word forms. We report two attempts to replicate this pattern, one with new materials, and one with Jescheniak and Levelt's orginal pictures. In both studies we found a strong WFE when the pictures were shown for the first time, but much weaker effects on their second and third presentation. Importantly these patterns were seen in both the picture naming and the gender decision tasks, suggesting that either word frequency does not exclusively affect word form retrieval, or that the gender decision task does not exclusively tap lemma access.

Examining Letter Detector Tolerance through Offset Letter Halves: Evidence from Lexical Decision.

Neurobiological models of reading assume that the specialized detectors at the letter level (e.g., the arrays of detectors for the letter 'n') possess a certain degree of tolerance (e.g., Local Combination Detectors model, Dehaene et al. 2005). In this study, we designed two lexical decision experiments that examined the limits of tolerance of letter detectors by introducing a novel manipulation involving shifting letter halves (e.g., in Experiment 1; in Experiment 2) relative to intact items. This manipulation alters the transition between upper and lower parts of the letters, adding junctions that do not exist in the intact letter forms. We included high- and low-frequency words in the stimulus list to investigate whether letter distortion affects processing beyond the letter level, reasoning that interactive effects would signal top-down lexical feedback. In Experiment 1, which employed a subtle letter shift, we observed a minimal cost of letter distortion that did not interact with word frequency. Experiment 2, employing a larger letter shift, revealed an overall greater reading cost that affected differentially high- and low-frequency words. Overall, these findings offer insights into the limits of resilience in letter detectors to distortion during word recognition and introduce a novel manipulation of letter distortion.

Lexical Access Restrictions after the Age of 80.

BACKGROUND: During the fourth age (80+ years), cognitive difficulties increase. Although language seems to resist the advancement of age, an older person without pathological developments in cognition may exhibit deficits in lexical access. This study examines the restrictions on lexical access in people aged 80 and older in word recognition and retrieval modalities through four lexical tasks. METHOD: The effect of aging on response time and accuracy was measured using recognition (lexical decision/naming/priming) and retrieval (picture naming) tasks. A fourth age group (>80) and two third age groups (60-69/70-79) were compared according to lexical access modality and type of task employed through linear regression models. RESULTS: People aged 80 and older exhibit a strong lexical access constraint, as they are slower and less accurate in recognizing and retrieving words than both third age groups. These restrictions are more profound for the word retrieval modality, especially in the picture naming task. CONCLUSION: Impaired fluid intelligence and internode transmission deficits during advanced aging could further reduce the ability to recognize and/or retrieve words, having an impact on access speed and accuracy. Furthermore, the idea that crystallized intelligence could strengthen the accuracy of lexical access during aging is supported, specifically in word recognition modality.

Language abilities, not cognitive control, predict language mixing behavior in bilingual speakers with aphasia.

PURPOSE: Language Mixing (LM) occurs among neurotypical bilinguals as well as among bilingual persons with aphasia (BiPWAs). The current study aimed to investigate whether LM in BiPWAs stems from a linguistic impairment, an impairment in cognitive control, or both. METHOD: Twenty Russian-Hebrew-speaking BiPWAs were split into two groups based on aphasia severity (Severe/Moderate vs. Mild). Frequencies and patterns of LM in narrative production by BiPWAs in L1-Russian and in L2-Hebrew were analyzed. To investigate the underlying mechanisms of LM, all participants completed linguistic background questionnaires, the Bilingual Aphasia Test (BAT) in both languages, and a battery of 10 cognitive tests. RESULTS: The results indicated an effect of aphasia severity and an effect of language. Higher LM frequency was observed in BiPWAs with severe/moderate aphasia symptoms as compared to BiPWAs with mild symptoms. In both groups, higher LM frequency was observed in L2-Hebrew narratives, the weaker post-stroke language for most participants in the sample. The results also showed qualitative LM differences in L1-Russsian and L2-Hebrew contexts. In L1-Russian narratives, BiPWAs mainly switched to L2-Hebrew nouns, while in L2-Hebrew narratives, they mainly inserted L1-Russian discourse markers and function words. CONCLUSIONS: Linguistic factors such as pre- and post-stroke self-rated language proficiency and level of language impairment due to aphasia were found to predict LM frequency in L1-Russian and in L2-Hebrew. Cognitive abilities did not predict LM frequency. Based on our findings, we suggest that LM behavior in BiPWAs might be primarily related to language skills in L1 and L2, rather than to cognitive control impairments.

Nonword reading by adults who stutter in a transparent orthography.

PURPOSE: Using word- and nonword-reading passages in Kannada, which has a transparent orthography, we attempted to determine (a) whether orthographic differences between English and Kannada may explain the observed differences in stutter rates on nonwords, and (b) whether longer nonwords, like words, incur higher rates of stutters. METHODS: Stutters are defined as sound or syllable repetitions, sound prolongations, broken words or nonwords (a pause within a word or nonword), abnormal pauses, and intrusive vowel-like sounds. Twenty-six persons, who stutter, read the word and nonword passages. The nonwords were created by changing the first syllable of each word; otherwise words and nonwords were equivalent in length and syllable structure. Stutters were counted from audio-recordings and statistically analyzed. RESULTS: PWS stuttered on words in varying amounts and in significantly larger amounts on nonwords. Stutter frequency increased roughly in proportion to the increase in the length of phonological words (previously known) and nonwords (reported for the first time here). CONCLUSION: The results cannot be attributed to the difficulty of pronouncing nonwords because Kannada orthography has a one-to-one relationship between the written and spoken forms of words. Speech production is a multi-stage process consisting of ideation, lemma selection, phonological word creation, and the articulatory planning and execution. Because nonwords lack meaning and clearly identifiable part of speech, it appears that stutters arise late in the speech production process at the phonological word formation and articulatory planning stages. Meaning, lexicality, and morphosyntax may not contribute significantly to the occurrence of stutters.

An Evidence Accumulation Account of Masked Translation Priming in Two Bilingual Populations.

This manuscript addresses the phenomenon of masked priming and the cognitive process of switching from Spanish to English while reading in sequential bilingual texts compared to heritage speakers. A lexical decision task was employed in the present study with masked translation priming, which serves as a valuable tool for elucidating the orthographic and lexical processes involved in the initial stages of reading. This study builds upon previous research conducted on monolingual masked priming, which consistently demonstrates shifts in the response time (RT) distributions when comparing related and unrelated primes. Within the framework of a diffusion model, we implemented two theoretical positions. First, we posited that translation priming operates at the orthographic level, resulting in enhanced efficiency during the encoding process. Second, we explored the possibility that translation priming operates at the semantic level, influencing the accumulation of evidence during the lexical decision task. The findings of the present study indicate that translation priming elicits outcomes similar to those observed in monolingual priming paradigms. Specifically, we observed that translation priming facilitation is manifested as shifts in the RT distributions. These findings are interpreted to suggest that the benefits derived from the encoding process are not specific to the accessed lexicon following a brief stimulus presentation.

Breaking the boundaries: the power of ligatures in visual-word recognition.

Introduction: Current neurobiological-inspired models of visual-word recognition propose that letter detectors in the word recognition system can tolerate some variations in the visual form of the letters. However, it is unclear whether this tolerance extends to novel ligatures, which combine two letters into a single glyph. Methods: To investigate this, the present study utilized a masked priming experiment with a lexical decision task to examine whether primes containing novel ligatures are effective in activating their corresponding base word, relative to omitted-letter primes, in the initial stages of word processing. For each target word (e.g., VIRTUAL), were created an identity prime (virtual), a prime containing a novel ligature of two of the letters (e.g., virtual; "ir" in a single glyph), and an omitted-letter prime where one letter was removed (e.g., vrtual [omitted-vowel] in Experiment 1; vitual [omitted-consonant] in Experiment 2). Results: Results showed that the presence of a novel ligature in the prime resulted in faster lexical decision times compared to a prime with an omitted vowel (Experiment 1), but not with an omitted consonant (Experiment 2). Furthermore, the performance with the primes containing the novel ligature was not different from that of the identity primes. Discussion: These results suggest that the word recognition system can quickly enable separate letter detectors for novel ligatures. These findings have important implications for our understanding of the front-end of visual-word recognition.

Practice beats age: co-activation shapes heritage speakers' lexical access more than age of onset.

Probabilistic associations make language processing efficient and are honed through experience. However, it is unclear what language experience factors explain the non-monolingual processing behaviors typical of L2 learners and heritage speakers (HSs). We investigated whether AoO, language proficiency, and language use affect the recognition of Spanish stress-tense suffix associations involving a stressed syllable that cues a present suffix (SALta "s/he jumps") and an unstressed syllable that cues a past suffix (SALtó "s/he jumped"). Adult Spanish-English HSs, English-Spanish L2 learners, and Spanish monolinguals saw a paroxytone verb (stressed initial syllable) and an oxytone verb (unstressed initial syllable), listened to a sentence containing one of the verbs, and chose the one they heard. Spanish proficiency measured grammatical and lexical knowledge, and Spanish use assessed percentage of current usage. Both bilingual groups were comparable in Spanish proficiency and use. Eye-tracking data showed that all groups fixated on target verbs above chance before hearing the syllable containing the suffix, except the HSs in the oxytones. Monolinguals fixated on targets more and earlier, although at a slower rate, than HSs and L2 learners; in turn, HSs fixated on targets more and earlier than L2 learners, except in oxytones. Higher proficiency increased target fixations in HSs (oxytones) and L2 learners (paroxytones), but greater use only increased target fixations in HSs (oxytones). Taken together, our data show that HSs' lexical access depends more on number of lexical competitors (co-activation of two L1 lexica) and type (phonotactic) frequency than token (lexical) frequency or AoO. We discuss the contribution of these findings to models in phonology, lexical access, language processing, language prediction, and human cognition.

Investigating the modulation of stimulus types on language switching costs: Do semantic and repetition priming effect matter?

Introduction: In the present study, I investigated the influence of stimulus types on bilingual control in the language switching process. The commonly employed stimuli in language switching studies - Arabic digits and objects - were compared to further investigate the way in which inhibitory control could be modulated by semantic and repetition priming effects. The digit stimuli have two unique characteristics in the language switching paradigm, for example, they are present repeatedly and are semantically related to each other, compared with pictural stimuli. Thus, these unique characteristics might influence the operation of inhibitory control in bilingual language production, modulating the size and asymmetry of switching costs. Methods: Two picture control sets were set up to match those characteristics: (1) a semantic control set, in which picture stimuli belong to the same category group, such as, animals, occupations or transportation and specific semantic categories were presented in a blocked condition; and (2) a repeated control set, in which nine different picture stimuli were repeatedly presented like the Arabic digits from 1 to 9. Results: When comparing the digit condition and the standard picture condition, analyses of naming latencies and accuracy rates revealed that switching costs were reliably smaller for digit naming than for picture naming and the L1 elicited more switching costs for picture naming than for digit naming. On the other hand, when comparing the digit condition and the two picture control sets, it was found that the magnitude of switching costs became identical and the asymmetry in switching costs became much smaller between the two languages.

A cautionary note on the studies using the picture-word interference paradigm: the unwelcome consequences of the random use of "in/animates".

The picture-word interference (PWI) paradigm allows us to delve into the process of lexical access in language production with great precision. It creates situations of interference between target pictures and superimposed distractor words that participants must consciously ignore to name the pictures. Yet, although the PWI paradigm has offered numerous insights at all levels of lexical representation, in this work we expose an extended lack of control regarding the variable animacy. Animacy has been shown to have a great impact on cognition, especially when it comes to the mechanisms of attention, which are highly biased toward animate entities to the detriment of inanimate objects. Furthermore, animate nouns have been shown to be semantically richer and prioritized during lexical access, with effects observable in multiple psycholinguistic tasks. Indeed, not only does the performance on a PWI task directly depend on the different stages of lexical access to nouns, but also attention has a fundamental role in it, as participants must focus on targets and ignore interfering distractors. We conducted a systematic review with the terms "picture-word interference paradigm" and "animacy" in the databases PsycInfo and Psychology Database. The search revealed that only 12 from a total of 193 PWI studies controlled for animacy, and only one considered it as a factor in the design. The remaining studies included animate and inanimate stimuli in their materials randomly, sometimes in a very disproportionate amount across conditions. We speculate about the possible impact of this uncontrolled variable mixing on many types of effects within the framework of multiple theories, namely the Animate Monitoring Hypothesis, the WEAVER++ model, and the Independent Network Model in an attempt to fuel the theoretical debate on this issue as well as the empirical research to turn speculations into knowledge.

Auditory Word Comprehension Is Less Incremental in Isolated Words.

Partial speech input is often understood to trigger rapid and automatic activation of successively higher-level representations of words, from sound to meaning. Here we show evidence from magnetoencephalography that this type of incremental processing is limited when words are heard in isolation as compared to continuous speech. This suggests a less unified and automatic word recognition process than is often assumed. We present evidence from isolated words that neural effects of phoneme probability, quantified by phoneme surprisal, are significantly stronger than (statistically null) effects of phoneme-by-phoneme lexical uncertainty, quantified by cohort entropy. In contrast, we find robust effects of both cohort entropy and phoneme surprisal during perception of connected speech, with a significant interaction between the contexts. This dissociation rules out models of word recognition in which phoneme surprisal and cohort entropy are common indicators of a uniform process, even though these closely related information-theoretic measures both arise from the probability distribution of wordforms consistent with the input. We propose that phoneme surprisal effects reflect automatic access of a lower level of representation of the auditory input (e.g., wordforms) while the occurrence of cohort entropy effects is task sensitive, driven by a competition process or a higher-level representation that is engaged late (or not at all) during the processing of single words.

Activating words without language: beta and theta oscillations reflect lexical access and control processes during verbal and non-verbal object recognition tasks.

The intention to name an object modulates neural responses during object recognition tasks. However, the nature of this modulation is still unclear. We established whether a core operation in language, i.e. lexical access, can be observed even when the task does not require language (size-judgment task), and whether response selection in verbal versus non-verbal semantic tasks relies on similar neuronal processes. We measured and compared neuronal oscillatory activities and behavioral responses to the same set of pictures of meaningful objects, while the type of task participants had to perform (picture-naming versus size-judgment) and the type of stimuli to measure lexical access (cognate versus non-cognate) were manipulated. Despite activation of words was facilitated when the task required explicit word-retrieval (picture-naming task), lexical access occurred even without the intention to name the object (non-verbal size-judgment task). Activation of words and response selection were accompanied by beta (25-35 Hz) desynchronization and theta (3-7 Hz) synchronization, respectively. These effects were observed in both picture-naming and size-judgment tasks, suggesting that words became activated via similar mechanisms, irrespective of whether the task involves language explicitly. This finding has important implications to understand the link between core linguistic operations and performance in verbal and non-verbal semantic tasks.

Do Diacritics Entail an Early Processing Cost in the Absence of Abstract Representations? Evidence from Masked Priming in English.

Using the masked priming technique, word recognition experiments in various languages have shown slower response times for a target word like NEVEU (nephew, in French) when preceded by a diacritical prime like néveu than by the identity prime neveu. The most common account of this effect is linguistic: diacritical and non-diacritical vowels (e.g., é and e) activate different letter representations (e.g., compare neveu /nə.vø/ vs. néveu /ne.vø/). However, another explanation is that the reduced effectiveness of the diacritical primes is merely due to the perceptual salience of accent marks in the first moments of word processing. Here, we designed a masked priming experiment that tested this perceptual salience account by comparing the effectiveness of diacritical versus non-diacritical primes in a language where diacritics have no linguistic value, namely, English (e.g., nórth-NORTH vs. north-NORTH). We found a small but reliable cost due to the diacritical primes, thus revealing that perceptual salience reduced the effectiveness of the primes. However, the effect sizes were substantially smaller than in the experiments in languages with diacritical marks, thus suggesting that the néveu-NEVEU versus neveu-NEVEU difference relies on both linguistic and perceptual sources.